ATRACTIB

OFFICIAL TITLE: PHASE II CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF FIRST LINE ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB (AVASTIN®) IN PATIENTS WITH ADVANCED OR METASTATIC TRIPLE-NEGATIVE BREAST CANCER 

SCIENTIFIC MEETINGS

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CLINICAL TRIAL DETAILS

THIS IS A MULTICENTRE, OPEN-LABEL, SINGLE-ARM, PHASE II CLINICAL TRIAL. MEN AND WOMEN AGE ≥ 18 YEARS WITH PREVIOUSLY UNTREATED UNRESECTABLE LOCALLY ADVANCED OR METASTATIC TRIPLE-NEGATIVE BREAST CANCER (TNBC) THAT IS NOT AMENABLE TO RESECTION WITH CURATIVE INTENT. PATIENTS IN THIS SINGLE-ARM STUDY (N=100) WILL RECEIVE TREATMENT (INTRAVENOUS INFUSION) WITH ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB (AVASTIN®).

 

THE MAIN OBJECTIVE IS TO EVALUATE THE EFFICACY –IN TERMS OF PROGRESSION-FREE SURVIVAL (PFS)– OF FIRST LINE ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB (AVASTIN®) IN PATIENTS WITH UNRESECTABLE LOCALLY ADVANCED OR METASTATIC TNBC.

ATRACTIB AT CLINICALTRIALS.GOV

TUMOR TYPE

PHASE

Breast

II

100

45

Spain, Italy, Portugal, France, Germany and UK

N

SITES

COUNTRY

STATUS

Recruitment closed

ESMO BREAST 2022 – DOWNLOAD THE POSTER

ATRACTIB SITES

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SPAIN

Hospital Arnau de Vilanova de Lleida

SPAIN

Hospital Universitario Ramón y Cajal

SPAIN

Hospital de Dènia Marina Salud

SPAIN

Hospital Clínico San Carlos

SPAIN

MD Anderson Cancer Center Madrid 

SPAIN

Hospital Universitario Miguel Servet

SPAIN

Complejo Hospitalario de Navarra 

SPAIN

Hospital Universitari Dexeus

SPAIN

Hospital de Sant Joan Despí Moisès Broggi

GERMANY

Städtisches Klinikum Dessau 
Zentrum für klinische Studien

GERMANY

Universitätsklinikum Essen
Klinik für Frauenheilkunde und Geburtshilfe

GERMANY

Medizinische Fakultät Mannheim der Universität Heidelberg Frauenklinik

SPAIN

Hospital Universitario Virgen del Rocío 

SPAIN

Complejo Hospitalario Ruber Juan Bravo

SPAIN

Hospital Universitari Sant Joan de Reus

SPAIN

Hospital Universitario San Juan de Alicante

SPAIN

Hospital Universitario La Ribera

SPAIN

Hospital Quirónsalud Valencia

SPAIN

Hospital Universitario Insular de Gran Canaria 

SPAIN

Hospital Universitario San Cecilio

ITALY

Istituto Oncologico Veneto IRCCS

ITALY

IRCCS - Istituto Nazionale dei Tumori Fondazione "G. Pascale"

FRANCE

Hopital Europeen Georges Pompidou

UK

Royal Cornwall Hospital - NHS Trust