ATRACTIB
OFFICIAL TITLE: PHASE II CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF FIRST LINE ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB IN PATIENTS WITH ADVANCED OR METASTATIC TRIPLE-NEGATIVE BREAST CANCER
CLINICAL TRIAL DETAILS
THIS IS A MULTICENTRE, OPEN-LABEL, SINGLE-ARM, PHASE II CLINICAL TRIAL. MEN AND WOMEN AGE ≥ 18 YEARS WITH PREVIOUSLY UNTREATED UNRESECTABLE LOCALLY ADVANCED OR METASTATIC TRIPLE-NEGATIVE BREAST CANCER (TNBC) THAT IS NOT AMENABLE TO RESECTION WITH CURATIVE INTENT. PATIENTS IN THIS SINGLE-ARM STUDY (N=100) WILL RECEIVE TREATMENT (INTRAVENOUS INFUSION) WITH ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB.
THE MAIN OBJECTIVE IS TO EVALUATE THE EFFICACY –IN TERMS OF PROGRESSION-FREE SURVIVAL (PFS)– OF FIRST LINE ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB IN PATIENTS WITH UNRESECTABLE LOCALLY ADVANCED OR METASTATIC TNBC.
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TUMOR TYPE
PHASE
Breast
II
100
26
Spain, Italy, France, Germany and UK
N
SITES
COUNTRY
STATUS
Analysis
PRESS RELEASE
SCIENTIFIC IMPACT
SABCS 2023 – DOWNLOAD THE PRESENTATION
SABCS 2023 – DOWNLOAD THE POSTER
SABCS 2023 – DOWNLOAD THE LAY LANGUAGE SUMMARY
ASCO 2022 – DOWNLOAD THE POSTER
ESMO BREAST 2022 – DOWNLOAD THE POSTER
TRIAL RESUME
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Medizinische Fakultät Mannheim der Universität Heidelberg Frauenklinik
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Hospital Universitario Virgen del Rocío
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Complejo Hospitalario Ruber Juan Bravo
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Hospital Universitari Sant Joan de Reus
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Hospital Universitario San Juan de Alicante
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Hospital Universitario La Ribera
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Hospital Quirónsalud Valencia
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Hospital Universitario Insular de Gran Canaria
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Hospital Universitario San Cecilio
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