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MiRaDor

OFFICIAL TITLE: A PROOF-OF-CONCEPT STUDY TO EVALUATE TREATMENTS' EFFICACY BY MONITORING MINIMAL RESIDUAL DISEASE USING CTDNA IN HR-POSITIVE/HER2-NEGATIVE EARLY BREAST CANCER POPULATION.

HR+/HER2- early breast cancer with high risk of relapse

II

40 (possible 20 patient expansion cohort)

67

Spain, England, Brazil, Peru, Italy, France, Poland, Greece

Set-up

CLINICAL TRIAL DETAILS

THE PRIMARY OBJECTIVE IS TO EVALUATE THE EFFICACY IN TERMS OF RATE OF PATIENTS WITH A 90% DECREASE OR CLEARANCE IN BASELINE CTDNA AT THREE MONTHS AFTER RANDOMIZATION.

IN ADDITION, THE STUDY WILL ASSESS THE EFFICACY IN TERMS OF THE RATE OF PATIENTS WITH A 90% DECREASE IN BASELINE CTDNA AT SIX, NINE AND TWELVE MONTHS, AS WELL AS ASSESS THE RATE OF PATIENTS WITH A 50% AND 70% DECREASE IN BASELINE CTDNA AT THREE, SIX, NINE AND TWELVE MONTHS.


MiRaDor AT CLINICALTRIALS.GOV

TUMOR TYPE

PHASE

N

SITES

COUNTRY

STATUS

MiRaDor SITES

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SPAIN

Hospital Universitario Clínico San Cecilio de Granada

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SPAIN

Hospital Clínic i Provincial de Barcelona

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SPAIN

Hospital Arnau de Vilanova de Valencia

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SPAIN

Complejo Hospitalario de Jaén

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SPAIN

Hospital General Universitario Dr. Balmis

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SPAIN

Hospital Universitario La Ribera, Alzira

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SPAIN

Hospital Virgen de los Lirios

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SPAIN

Hospital Marina Salud de Denia

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SPAIN

Hospital de Sagunto

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SPAIN

Hospital Universitario Virgen del Rocío

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SPAIN

Hospital Universitari Sant Joan de Reus

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SPAIN

Hospital Universitari Dexeus

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SPAIN

Hospital Universitario de Basurto

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SPAIN

Hospital Universitario Arnau de Vilanova de Lleida

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SPAIN

Hospital de Manises

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ENGLAND

Barts Cancer Institute

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ENGLAND

Centro de Câncer de Brasília

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BRAZIL

Belo Horizonte (Oncocentro)

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